Semiparametric inferences for association with semi-competing risks data

Semi-parametric inferences for association with semi-competing risks data.

In many biomedical studies, it is of interest to assess dependence between bivariate failure time data. We focus here on a special type of such data, referred to as semi-competing risks data. In this article, we develop methods for making inferences regarding dependence of semi-competing risks data across strata of a discrete covariate Z. A class of rank statistics for testing constancy of asso...

Semi-Competing Risks Data Analysis

Hospital readmission is a key marker of quality of healthcare; it has been used to investigate variation in quality among patients in a broad range of clinical contexts and has become an important policy measure. Notwithstanding its widespread use, however, readmission remains controversial as a measure of quality. Among the concerns raised, whether and how patient deaths are handled in the ana...

Semiparametric analysis of mixture regression models with competing risks data.

In the analysis of competing risks data, cumulative incidence function is a useful summary of the overall crude risk for a failure type of interest. Mixture regression modeling has served as a natural approach to performing covariate analysis based on this quantity. However, existing mixture regression methods with competing risks data either impose parametric assumptions on the conditional ris...

Nonparametric estimation with left truncated semi-competing risks data

SUMMARY Cause-specific hazard and cumulative incidence function are of practical importance in competing risks studies. Inferential procedures for these quantities are well developed and can be applied to semi-competing risks data, where a terminating event censors a non-terminating event, after coercing the data into the competing risks format. Complications arise when there is left truncation...

SEMIPARAMETRIC ESTIMATORS IN COMPETING RISKS REGRESSION by